[[4-(trifluoromethyl)phenyl]amino]ammonium chloride
4-(Trifluoromethyl)phenylhydrazine hydrochloride
CAS: 2923-56-0
Molecular Formula: C7H8ClF3N2
[[4-(trifluoromethyl)phenyl]amino]ammonium chloride - Names and Identifiers
| Name | 4-(Trifluoromethyl)phenylhydrazine hydrochloride |
| Synonyms | [4-(trifluoromethyl)phenyl]hydrazine 4-(Trifluoromethyl)phenylhydrazine HCl [4-(trifluoromethyl)phenyl]diazanium chloride 4-trifluoromethylphenylhydrazinehydrochlroide 4-trifluoromethylphenyl hydrazine hydrochlroide 4-(TRIFLUOROMETHYL)PHENYLHYDRAZINE HYDROCHLORIDE 4-(Trifluoromethyl)phenylhydrazine hydrochloride [[4-(trifluoromethyl)phenyl]amino]azanium chloride [[4-(trifluoromethyl)phenyl]amino]ammonium chloride N'-(4-TRIFLUOROMETHYL-PHENYL)-HYDRAZINIUM, CHLORIDE 1-[4-(TRIFLUOROMETHYL)PHENYL]HYDRAZINE HYDROCHLORIDE 1-[4-(Trifluoromethyl)phenyl]hydrazine hydrochloride (4-(trifluoromethyl)phenyl) hydrazine hydrochloride |
| CAS | 2923-56-0 |
| EINECS | 642-499-3 |
| InChI | InChI=1/C7H7F3N2.ClH/c8-7(9,10)5-1-3-6(12-11)4-2-5;/h1-4,12H,11H2;1H |
[[4-(trifluoromethyl)phenyl]amino]ammonium chloride - Physico-chemical Properties
| Molecular Formula | C7H8ClF3N2 |
| Molar Mass | 212.6 |
| Melting Point | 200 °C |
| Boling Point | 230°C at 760 mmHg |
| Flash Point | 92.9°C |
| Vapor Presure | 0.0674mmHg at 25°C |
| Appearance | White solid |
| Storage Condition | under inert gas (nitrogen or Argon) at 2-8°C |
| MDL | MFCD00204233 |
| Use | Applied to pharmaceutical intermediates. |
[[4-(trifluoromethyl)phenyl]amino]ammonium chloride - Risk and Safety
| Hazard Symbols | Xi - Irritant |
| Risk Codes | R20/21/22 - Harmful by inhalation, in contact with skin and if swallowed. R36/37/38 - Irritating to eyes, respiratory system and skin. |
| Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection. S37/39 - Wear suitable gloves and eye/face protection |
| HS Code | 29280000 |
| Hazard Class | IRRITANT |
[[4-(trifluoromethyl)phenyl]amino]ammonium chloride - Introduction
4-(Trifluoromethyl)phenylhydrazine hydrochloride is an organic compound with the chemical formula C7H3F3N2 · HCl. The following is a description of its nature, use, preparation and safety information:
Nature:
-Appearance: White to light yellow crystalline powder
-Molecular Weight: 232.56
-Melting Point: 142-145 ° C
-Solubility: Dissolved in water and alcohol, insoluble in non-polar solvents
Use:
4-(Trifluoromethyl)phenylhydrazine hydrochloride has a wide range of applications in organic synthetic chemistry:
-It can be used as a reagent for organic reactions, such as the synthesis of amino acids, Catalyst synthesis, etc.
-It can also be used as a synthetic intermediate for organic dyes.
Method:
In General, 4-(Trifluoromethyl)phenylhydrazine hydrochloride can be prepared by the following steps:
1. 4-Nitrotoluene is reacted with trifluoromethanesulfonic acid to obtain 4-trifluoromethyltoluene.
2. 4-Trifluoromethyltoluene reacts with hydrazine to generate 4-trifluoromethylphenylhydrazine.
3. Finally, 4-trifluoromethylphenylhydrazine is reacted with hydrochloric acid to obtain 4-(Trifluoromethyl) phenol hydrochloride.
Safety Information:
- 4-(Trifluoromethyl)phenylhydrazine hydrochloride is a chemical that needs to follow relevant safety procedures and maintain appropriate laboratory safety measures.
-Wear appropriate personal protective equipment such as lab gloves, goggles, etc. when handling the compound.
-Avoid inhaling its dust or contact with skin, eyes and clothing to prevent irritation or injury.
-Avoid contact with oxidants and strong acids during storage and handling to avoid reaction.
-If swallowed or inhaled, seek medical attention immediately. If skin or eye contact occurs, rinse with plenty of water for at least 15 minutes and seek medical attention.
Nature:
-Appearance: White to light yellow crystalline powder
-Molecular Weight: 232.56
-Melting Point: 142-145 ° C
-Solubility: Dissolved in water and alcohol, insoluble in non-polar solvents
Use:
4-(Trifluoromethyl)phenylhydrazine hydrochloride has a wide range of applications in organic synthetic chemistry:
-It can be used as a reagent for organic reactions, such as the synthesis of amino acids, Catalyst synthesis, etc.
-It can also be used as a synthetic intermediate for organic dyes.
Method:
In General, 4-(Trifluoromethyl)phenylhydrazine hydrochloride can be prepared by the following steps:
1. 4-Nitrotoluene is reacted with trifluoromethanesulfonic acid to obtain 4-trifluoromethyltoluene.
2. 4-Trifluoromethyltoluene reacts with hydrazine to generate 4-trifluoromethylphenylhydrazine.
3. Finally, 4-trifluoromethylphenylhydrazine is reacted with hydrochloric acid to obtain 4-(Trifluoromethyl) phenol hydrochloride.
Safety Information:
- 4-(Trifluoromethyl)phenylhydrazine hydrochloride is a chemical that needs to follow relevant safety procedures and maintain appropriate laboratory safety measures.
-Wear appropriate personal protective equipment such as lab gloves, goggles, etc. when handling the compound.
-Avoid inhaling its dust or contact with skin, eyes and clothing to prevent irritation or injury.
-Avoid contact with oxidants and strong acids during storage and handling to avoid reaction.
-If swallowed or inhaled, seek medical attention immediately. If skin or eye contact occurs, rinse with plenty of water for at least 15 minutes and seek medical attention.
Last Update：2024-04-10 22:29:15
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